lung cancer

Latest Headlines

Latest Headlines

Clovis looks to rebuild the case for its cancer drug at FDA panel

Clovis Oncology, whose market value has plummeted by more than 80% over the past year, has secured a date with FDA advisers to make the case that its lung cancer treatment merits approval despite some disappointing data.

Qiagen backs liquid biopsy startup Exosome in $60M Series B

Diagnostics giant Qiagen has joined the syndicate of Exosome Diagnostics--helping to distinguish this liquid biopsy startup from its growing crowd of peers. The pair are already partnered under a 2014 lung cancer diagnostic development deal. The Cambridge, MA-based startup has raised a $60 million Series B round to launch its liquid biopsy test via its CLIA-certified lab as well as to seek out companion diagnostics deals with biopharmas.

Boehringer grabs 'breakthrough,' plots pivotal trials for rival to AstraZeneca, Clovis

The FDA is putting an oral lung cancer drug from Boehringer Ingelheim on its inside track, promising to accelerate development of a new EGFR mutation-specific tyrosine kinase inhibitor that could quickly rival competing therapies from AstraZeneca and Clovis Oncology. And Boehringer is promising to hustle its way through a pivotal program with an eye to a near-term launch.

AstraZeneca hit with setback as durvalumab falls further behind on lung cancer

AstraZeneca has run into another setback on its marquee cancer drug development effort. The pharma giant says its latest read on a study of durvalumab, a PD-L1 checkpoint inhibitor, indicates that investigators won't come out with the data needed to gain a fast approval to use it as a solo therapy to fight lung cancer.

Roche wins FDA approval for a new lung cancer drug

Roche picked up an accelerated FDA approval for its latest lung cancer therapy, planning to market the treatment for severely ill patients while building the clinical case for wider use.

Pfizer nabs speedy FDA review for new use of lung cancer med Xalkori

Pfizer's Xalkori is already used to treat patients with metastatic non-small cell lung cancer whose tumors are ALK-positive. But now it's on its way to snagging a speedy nod in another group of NSCLC patients, too.

UPDATED: Clovis Oncology shares crash after lung cancer response rate deteriorates

Clovis Oncology says that the FDA demanded fresh efficacy data for the lung cancer drug rociletinib (CO-1686) in order to complete its review. And while the biotech plans to hand that over today, it adds that the fresh data include a worse response rate than expected and could force a delay in the accelerated March 30, 2016, deadline that the FDA had set for a marketing decision.

Merck's star oncology drug posts mixed results in a lung cancer trial

Merck's immuno-oncology treatment Keytruda met just one of its two goals in a late-stage lung cancer trial, a rare clinical hiccup as it works to keep pace with rival Bristol-Myers Squibb and fortify its position as more contenders move toward the market.

Bristol-Myers' latest PD-1 win could pave the path to earlier use

Bristol Myers-Squibb, a leader among companies at work in immuno-oncology, is pressing for wider use of its lead treatment with new data showing the injected drug could succeed as part of a first-line treatment in lung cancer.

Exosome Diagnostics reels in $17.6M for liquid biopsy development

Exosome Diagnostics raked in $17.6 million in a second round of Series B financing, bringing the total amount raised to $44.7 million. The company plans to use the funds to support the launch of a few of its products, including two blood-based lung cancer liquid biopsies, a urine-based prostate cancer liquid biopsy and a solid tumor panel.